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Whether the breadth translates to clinical benefit on intact human skin depends entirely on whether the molecule reaches the cells whose gene expression it modulates

10.1038/ncomms11624 [DOI] [PMC free article] [PubMed] [Google Scholar] Korshunov KS, Blakemore LJ, Trombley PQ (2017) Dopamine: a modulator of circadian rhythms in the central nervous system

Other lines of evidence also suggest that GLP-1 may have additional effects other than the well-known acute insulin secretion stimulation

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